Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gnrh1  gonadotropin releasing hormone 1   (Synonyms: LHRH, LNRH)
Results	Reference
1*	J:310863 Cho HJ, Shan Y, Whittington NC, Wray S, Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome. Front Cell Dev Biol. 2019;7:121
1	J:141766 Chung WC, Moyle SS, Tsai PS, Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons. Endocrinology. 2008 Oct;149(10):4997-5003
1	J:127370 Cogliati T, Delgado-Romero P, Norwitz ER, Guduric-Fuchs J, Kaiser UB, Wray S, Kirsch IR, Pubertal Impairment in Nhlh2 Null Mice Is Associated with Hypothalamic and Pituitary Deficiencies. Mol Endocrinol. 2007 Dec;21(12):3013-3027
1	J:204657 Forni PE, Bharti K, Flannery EM, Shimogori T, Wray S, The indirect role of fibroblast growth factor-8 in defining neurogenic niches of the olfactory/GnRH systems. J Neurosci. 2013 Dec 11;33(50):19620-34
1	J:168231 Forni PE, Fornaro M, Guenette S, Wray S, A role for FE65 in controlling GnRH-1 neurogenesis. J Neurosci. 2011 Jan 12;31(2):480-91
1	J:171903 Forni PE, Taylor-Burds C, Melvin VS, Williams T, Wray S, Neural Crest and Ectodermal Cells Intermix in the Nasal Placode to Give Rise to GnRH-1 Neurons, Sensory Neurons, and Olfactory Ensheathing Cells. J Neurosci. 2011 May 4;31(18):6915-27
1*	J:98364 Gamble JA, Karunadasa DK, Pape JR, Skynner MJ, Todman MG, Bicknell RJ, Allen JP, Herbison AE, Disruption of ephrin signaling associates with disordered axophilic migration of the gonadotropin-releasing hormone neurons. J Neurosci. 2005 Mar 23;25(12):3142-50
1*	J:65758 Kramer PR, Wray S, Midline nasal tissue influences nestin expression in nasal-placode-derived luteinizing hormone-releasing hormone neurons during development. Dev Biol. 2000 Nov 15;227(2):343-57
1	J:174086 Layman WS, Hurd EA, Martin DM, Reproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome. Hum Mol Genet. 2011 Aug 15;20(16):3138-50
1	J:177773 Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P, Dysregulation of Semaphorin7A/beta1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility. Hum Mol Genet. 2011 Dec 15;20(24):4759-74
1*	J:203635 Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N, Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet. 2013 May 2;92(5):725-43
1	J:276971 Saadi H, Shan Y, Marazziti D, Wray S, GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice. Front Cell Neurosci. 2019;13:200
1	J:309185 Shan Y, Saadi H, Wray S, Heterogeneous Origin of Gonadotropin Releasing Hormone-1 Neurons in Mouse Embryos Detected by Islet-1/2 Expression. Front Cell Dev Biol. 2020;8:35
1	J:301210 Taroc EZM, Katreddi RR, Forni PE, Identifying Isl1 Genetic Lineage in the Developing Olfactory System and in GnRH-1 Neurons. Front Physiol. 2020;11:601923
1	J:283398 Taroc EZM, Naik AS, Lin JM, Peterson NB, Keefe DL Jr, Genis E, Fuchs G, Balasubramanian R, Forni PE, Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell Formation, and GnRH-1 Neuronal Migration. J Neurosci. 2020 Jan 8;40(2):311-326
1*	J:207824 Tiong JD, Pakiam JG, Wray S, Gonadotropin releasing hormone-1 expression in incisors of mice. Endocrinology. 2004 Aug;145(8):3608-12
1	J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81
1*	J:193307 Wray S, Nieburgs A, Elkabes S, Spatiotemporal cell expression of luteinizing hormone-releasing hormone in the prenatal mouse: evidence for an embryonic origin in the olfactory placode. Brain Res Dev Brain Res. 1989 Apr 1;46(2):309-18